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For more infomation >> Plainfield Sewer Cleaning | 815-630-1024 | Plainfield IL Sewer Cleaning - Duration: 1:08.

-------------------------------------------

SOMA Lore: Dr. Catherine Chun (Ft. Traggey & TrollForce) - Duration: 6:19.

Catherine Chun is probably the most important character in the game.

She's the one who talks with you, who plays as Simon Jarrett.

Her answers to Simon's cluelessness on his world around him and the discussions had with

Catherine, make this game what it is.

Sense Catherine Chun is such an important role to the game, it's obvious some people

are going to be a little curious on her background.

So sit back, and relax, as we cover Dr. Catherine Chun's background momentarily.

Before I begin, like, share, converse in the comments, subscribe for more lore and hit

the notification button on my channel beside the subscribe button, so you don't miss

my newest horror game lore.

Without further ado, let's begin our lore on the Dr. Catherine Chun in SOMA.

Dr. Catherine Chun was a Systems Engineer on Pathos II.

Catherine is a quiet, shy, asocial kind of person.

This is further proven by her insecure thoughts that all the co-workers disliked her, even

though she is a likable person to Simon Jarrett.

Catherine lived in Taipei, before the surface of Earth was destroyed by the comet.

Not much was known about her life before the disaster, but in one cutscene she states that

when she was little, she used to climb the stairs all the way to the roof of a building

and watch the streets of Taipei, stating she felt a profound feeling of connection with

the world.

That's all we really know on her early life.

Fast forwarding to her time on Pathos II, she began work on a project named "The Ark".

This Ark would be a matrix-like cyber world where people on brain scans could live in

a paradise even after Planet earth was destroyed.

After receiving knowledge of Imogen Reed's testings on the Vivarium prototype model,

Catherine studies it and sees that the WAU had used her capsule's concept to create

a scene around it's Imogen Reed model, it was a perfect scan of Imogen's real self,

to create a complete simulation of the testing room.

Using this concept, she created the first stages of the ARK project.

Once, Catherine showcased her project to co-workers of PATHOS-II, everyone was encouraged to have

their own brains scanned, so they could live on in the ARK when the Omega Space Gun launched

into outer-space, Catherine was the first to be scanned and this.. where things take

a pretty dark turn..

Mark Sarang, an employee of PATHOS-II, suggested suicide so they could quote "live on"

in the ARK.

Later on, Sarang actually commited suicide to make sure he lived on in the ARK.

After this, Catherine's co-workers began to doubt the project.

Later on, as the ARK project was nearly complete, Catherine and her new team, Sarah Lindwall,

Ian Pedersen, Nicolai Ivashkin and Jasper Hill, went to Site Phi, bringing the ARK along

with them to finally launch the ARK using the space gun.

Things didn't go as Catherine planned as the team divided from debates that the ARK

wouldn't survive the launch.

Catherine and Pedersen, got in a big argument.

Pedersen insisted keeping it in the station safe while Catherine was desperate to launch

it.

This caused a brawl between the two, resulting in injury to Catherine, which we'll cover

more on, later.

Fast forward a while later, a brain scan of many of the famous Simon Jarrett, awoke on

Upsilon and came across the control center and manages to reactivate Upsilon's reactors.

Catherine contacts Simon via the terminals in the control room and directs him to the

communication center.

There they commute and Catherine finds out Simon has no knowledge of the world around

him.

As the center started to collapse, Catherine quickly informs Simon to head to site Lambda,

where they could meet in person.

When Simon arrives, he hears Catherine down a corridor, telling him to not look at one

of the WAU infested monster.

After Simon avoids it, he heads to where Catherine's voice was heard from.

There, sit, a damaged machine, having been attacked by the Flesher.

No human like Simon was hoping to see.

When Simon reactivated the Reactors in Upsilon, it is believed to have reactivated this brain

scan of Catherine Chun.

Catherine informs Simon in a silly manner, that he's being a hypocrite, being a walking-talking

robot himself.

Sense this scan of Catherine was copied before the incident of her death, she has no recollection

of the brawl with Pedersen.

This brawl between the Catherine and Pedersen actually resulted in Catherine being killed

by blunt force trauma by a wrench swung at her head from Pedersen.

The rest of the team did an immoral act, calling it a simple "accident" and left her body

on site Phi to going back to site Tau, to figure out a new plan.

So, maybe Catherine was kind of right, about her co-workers disliking her, sadly enough.

They just left her body at Phi to rot away.

Throughout the game, Simon and Catherine create this bond together, talking about their fake

memories of being a human.

Talking about their experiences before the comet struck planet Earth.

They question what it means to be human, what they are, and what really happens when someone's

mind is quote "transferred over".

When Simon reaches site Phi near the ending of the game, he comes across Catherine's

real body.

There Catherine figures out she was killed by Pedersen, being shaken.

At the end of SOMA, Simon and Catherine proceed to launch the ARK and await their transfer.

This is where the game ends on a very sad note.

Catherine has to explain to Simon again there is no transfer, only a copy paste of one's

consciousness.

On the ARK, that has successfully launched, the other copy of Simon and Catherine, meet

finally, in some human form, even if it isn't a real world.

If you enjoyed my lore video on the Catherine Chun, hit like, share and hit that notify

button on my channel!

Also, I hoped you enjoyed the other's narrations.

I'm trying to make my channel more of a hub for the Frictional Games community, and

survival horror game community as a whole.

Subscribe for more creepy, eerie and disturbing horror game lore videos and I will see you

around!

For more infomation >> SOMA Lore: Dr. Catherine Chun (Ft. Traggey & TrollForce) - Duration: 6:19.

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Life gets more powerful with "Habits " @lifeasusualblog - Duration: 3:23.

Today I want to talk about why investing

a little bit of willpower can have a lot of upside

Welcome to Life As Usua,l a

video blog dedicated to making you a

more impactful leader the ideas of

execution self-awareness and direction

and today I want to talk about why

investing a little bit of willpower can

create a lot of upside for you. And what

are you investing that willpower in?

Habit. Habits are important because they

create an ability for you to get things

done without investing any willpower.

That saves you and your willpower from

dealing with smaller problems and

tackling more complex problems. Solving

complex problems means you're a way more

impactful of a leader than somebody that solves simple things

Habits don't just

appear out of nowhere, they take work.

Some of the habits that we've built over

life, things like brushing your teeth and

making your bed, are really good to keep.

There are other habits such as

checking your email every five minutes

or going to get a burger after work are

bad. Now it takes some time to really

change those habits and I'd like to

recommend the book to you called The

Power of Habit from Charles Duhigg. That

would really help with that but we're

not focusing on that for now. The focus

for the video is for you to understand

that using habits and having intention

with those habits are the key for you

being a more impactful leader because

habits save you time. Let me give you an

example: the habit I built over the last

year and a half

was writing a blog every day. This took

a lot of work and almost took me three

or four years of starting and stopping

to get to the point where I've built

this habit every day but now rain or

shine I write.

What has this done for me? Well it has

helped clarify my thinking. Me clarifying

my thinking has helped me solve more

complex problems that people have and

whenever I mentor somebody or whenever

somebody has a question I can direct

them to a blog post that I've written

that can help them far more than me

talking on the phone.That's the power of

habit and now have a thousand posts on

my blog and more coming. So here's the

point investing that willpower is a

way you can create some real upside to

help you solve complex problems use your

habits to give you a willpower to be an

impactful leader to solve complex

problems instead of being trapped by

them. So my challenge this week think of

three habits that you can add to your

repertoire to do something then out of

those three pick one and just make the

promise to yourself that you are going

to invest willpower specifically to

build that habit once you've made that

decision send me an email with habit in

the subject line and we could start a

discussion you'll find my email in the

description.

For more infomation >> Life gets more powerful with "Habits " @lifeasusualblog - Duration: 3:23.

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(Liberian Music 2017) PROVAI ft SKOB & GIZMO - GO GAGA - Duration: 5:00.

Please Like, Comment, Share & Subscribe

For more infomation >> (Liberian Music 2017) PROVAI ft SKOB & GIZMO - GO GAGA - Duration: 5:00.

-------------------------------------------

Train Your Brain To Let Go Of Habits – 10 Methods For Creating New Neural Pathways - Duration: 7:33.

Train Your Brain To Let Go Of Habits � 10 Methods For Creating New Neural Pathways

By consciousreminder

When you understand how neural pathways are created in the brain, you get a front row

seat for truly comprehending how to let go of habits.

Neural pathways are like superhighways of nerve cells that transmit messages. You travel

over the superhighway many times, and the pathway becomes more and more solid. You may

go to a specific food or cigarettes for comfort over and over, and that forms a brain pathway.

The hopeful fact, however, is that the brain is always changing and you can forge new pathways

and create new habits. That�s called the neuroplasticity of the brain.

I used to drive with one foot on the brake and the other on the accelerator, and I wanted

to train myself to drive with one foot only. It took some time, as I had a strong neural

pathway for two-footed driving. But because I had the will to do it, I built a new pathway,

and I rewired or reprogrammed my brain. You can remove a behavior or thought or addictions

directly from the brain.

Because of neuroplasticity, the brain�s ever-changing potentials, anything is possible.

People who�ve had strokes can retrain their brains to function again by building new pathways.

Smokers and overeaters and many others can learn new behaviors and attitudes and can

transform their lives.

Whether you work with others on their habits or you work with your own (or both), you can

apply these understandings to boost your success.

Some Powerful Ways to Retrain the Brain:

1. Identity the habit you�d like to transform and set the intention.

You may remember the punch line �The light bulb has to want to change.� You have to

have a high intention to change as well. If there is this high intention, then creating

new pathways in your brain is bound to happen.

2. Observe what the old habit or pathway is doing in your life.

Look at feelings, thoughts, and how the body is responding to the habit, and see what results

you�re creating in your life. Be the witness, and be aware.

3. Shift your focus.

This is very important. To create a new neural pathway, you take the focus off the old habit,

and then that old habit eventually falls away. Don�t pay attention to the donuts and cakes.

Take your awareness and focus it on good, wholesome, healthy delicious foods.

4. Use your imagination.

You can build new neural pathways not only with new behaviors, but through the imagination.

Just imagine the new behaviors over and over and over. Keep repeating that in your mind

so you build new pathways. Focus your mind and retrain your brain.

5. Interrupt your thoughts and patterns when they arise.

Say �no� or �cancel� when an old thought or impulse comes in, and say, �I don�t

have to do that anymore.� Then turn toward the new neural pathway you�re building and

keep on going in the right direction.

6. Use aversion therapy.

This isn�t everyone�s cup of tea. It�s an optional path. I like to call it �the

maggots on the chocolate cake technique.� I used to love candies and sweets, and when

I stopped eating them, I still had to pass by them when I walked by the candy store in

town. I used aversion to train my brain to walk on by: �That�s junk,� I said to

myself. �It�s made in factories, sickeningly sweet, makes me feel bad. The company makes

it so sweet just to addict buyers. I don�t want any of that.� So I talk myself out

of it. I�ve use it with many clients (only those who say they want it) on smoking, junk

food, cocaine and many other behaviors.

7. Create a specific plan and choose what to do instead.

When you get specific, it�s easier to build new neural pathways. You �make it official.�

Decide if you want to exercise instead of overeating or if you want to eat fruit instead

of candy. Just keep focused on the new choice. You may want to create affirmations and anchors

to reinforce your choices. This can be �I�m free or �I�m in control.� Reinforce

this with energy therapies like EFT or other techniques.

8. Transform the obstacles.

Look at what�s in the way. Look at secondary gain � what you�ve been getting out of

the old habits or pathways. Look at the stress in your life and how you can handle it differently.

Get your mind in the place of possibility. Handle the emotions and thoughts and get on

a new superhighway in your mind.

9. Connect with your Higher Source for inspiration and support.

Listen to our guidance. Know you have the Force within you, and therefore you have great

power. Meditation creates new pathways and brain changes. Actual studies have been done

on the brains of monks to show meditation�s effect on neural circuits of the brain.

10. Transform and make the shift.

Know that transformation is always possible and that you can create new brain pathways

whenever you�re ready to make the shift. When you keep your mind in the �I can do

it!� space, you get a clear sense that you�re done with the old and on a new beam now.

Some people feel we�re being rewired spiritually for anew era. There�s great upheaval now

in our world. And there�s a process of transformation happening on earth in which huge changes are

taking place for all of humanity. You have to be present in the moment, overcome your

fears, and get to know the Infinite source so you can be a vehicle for

the light to predominate on the earth.

For more infomation >> Train Your Brain To Let Go Of Habits – 10 Methods For Creating New Neural Pathways - Duration: 7:33.

-------------------------------------------

(Liberian Music 2017) OBE NIZE - RISE Official Video - Duration: 2:15.

Please Like, Comment, Share & Subscribe

For more infomation >> (Liberian Music 2017) OBE NIZE - RISE Official Video - Duration: 2:15.

-------------------------------------------

Очень интересный цветок ирис - Duration: 2:19.

For more infomation >> Очень интересный цветок ирис - Duration: 2:19.

-------------------------------------------

Havana Vieja e Balada - EP 03 - Duration: 14:05.

Third day in Havana, we are gonna exchange money. The line is a bit long!!

You have to bring your passport. Then the person will give you a piece of paper with the total amount and how

many and which bills and coins you are gonna get, then you get the CUCs. After this you can exchange the CUC by Cuban Pesos.

1 CUC can be exchanged for almost US$ 1,00. Meanwhile, 1 CUC can be exchanged for 24 Cuban Pesos.

1 Cuban Peso is the same as US$ 0,04. But you can have lunch for 30 Cuban Pesos, which is like US$ 1,20.

Really cheap if you are using Cuban Pesos!!

Yesterday we were supposed to party, but apparently on the weekends you have to get there really early,

otherwise it is gonna be full and you can't get in. At around 8PM we bought a bottle of rum and started

doing drinking games. When we realised, it was around 11PM already, so we didn't go out.

Yesterday we didn't go out, but tonight we are gonna go!! Today is a day for... - Party

Breakfast with Rafa.

We found this cuban Shopping Mall to see how it is, if it is anyhow differente, but as you can see, it isn't

that differente from any Shopping Mall anywhere else. Obviously a small Shopping Mall and from a

poor country, but not that different. Now we are gonna get out and keep walking to the train station.

Yesterday we found out that you can travel by train in Cuba, but the train breaks all the time.

So it is a nice experience, but dangerous. What we are gonna do is to go to the train station, as tomorrow

we are gonna go to Viñales and I found out that there is a train to Viñales. Here in Cuba you should only get a

train if it is a short distance. Actually, they say you shouldn't get a train at all. But let's see the prices.

- Hello. Tomorrow we wanna go to Viñales and we would like to know what time, how much and how long it takes by train.

- Pinar del Rio. - Sorry?

- Pïnar del Rio? - Si, si. Pinar del Rio.

- Tomorrow at 7AM. From the train station next to this one.

- Should we pain when inside of the train? - You have to be there at 6AM or 6.30AM to buy the ticket.

- How long is the trip? - It leaves at 7AM and gets there at 2PM.

- How much is it? - 5 Cuban Pesos. For you CUC 5.

- Thanks. - Where are you from?

- Brazil. - Do you like Brazil?

- Of course!! - The soap opera that is playing...

- Here all the soap operas are from Brazil. - Yeah, in the place we are staying we saw the soap opera "Vítimas"...

- Mentiras something... Rastro de Mentiras!! - I am watching...

- Nico is a... - I am watching... No, but my favourite brazilian girl is Pitanga.

- She is my favourite. - She is THE brazilian woman.

- She is my favourite. All of them are good, but the one I like the most, how she works, is Pitanga.

- Here in Cuba we say La Pitanga.

- Well, good luck and have a nice day. - You too.

We are not taking a train for sure. There are two other options... Three, actually...

We can take a "Guagua", which is the local bus, cheaper. We can take a Viazul bus, which is for tourists and

expensive. This options is not gonna happen also. Or we can take a shared taxi.

More people who are going to the same place, so they share the taxi.

It costs around CUC 10 each and it takes like 2h to get there.

Now the idea is to walk around Havana Vieja, the most touristic place in Havana.

So we are in Havana Vieja and behind me is the Capitolio.

Some people believe that Raul Castro lives there, but actually he doesn't. He is at the Plaza de la Revolución.

There are some ministries. Here is actually a museum that they are fixing.

It looks like it is closed for restoration.

One of the most touristic things here is to take an old taxi like this and go around the city.

- Now we are going to the Museum of the... - Revolution.

Those are bullet holes. In 1957 some revolutionary students attacked Fulgêncio Batista. This was actually

the government palace. They attacked him. They didn't succeed, as Fulgêncio Batista only scaped from Cuba in 1959.

Fidel came here, took the palace and started to rule the country. It was here in this room where Che Guevara was

turned into a cuban citizen, as he was from Argentina.

We just left the Museum of the Revolution. So, are you feeling revolutionary?

Yes, I am. I am ready. Just invite me and I will do it.

So it is a really basic museum, full of pictures and text. There aren't any videos, but it is interesting.

The first floor only has the ticket entrance. The second floor shows the post-revolutionary period.

Which were the first actions of the government, like turning into public property everything that

belonged to the pro-Batista people and to the americans also. One curiosity is that the americans supported

the revolution, thinking that like this they would bring more democracy to Cuba, but when the revolutionary

started making everything State property, then the americans became against it.

The second floor shows the story of the revolutionaries before the revolution. The main ones, not all of them,

like Camilo Cienfuegos, Che, Fidel, also talks about some women that participated in the revolution.

And here they show the Bastards Corner. The first one is Fulgêncio Batista, the dictator before the revolution.

Ronald Reagan, which started the anti-communist actions here.

Bush father and Bush son, a bit nazi and also stupid, reading the book upside down.

From there you can access the Granma Memorial, which shows the Yatch Granma. For those who don't know,

Granma was the yatch used by the cuban revolutionaries in 1956 to come from the Gulf of Mexico to Cuba.

It is made for 12 people, but 82 people came on it, including Fidel and Raul Castro, Che Guevara and Camilo Cienfuegos.

They got in Cuba in a place nowadays called Granma, which is also the same place where Jose Martí

landed 61 years before to fight for the Cuban independence from Spain, so this made a poetic sense

to the landing of the yatch Granma. This is the story they tell in the museum.

Of course there is no criticism to the revolution as we are in a dictatorship. But you can always check on

Google to see if those informations are correct and have your own conclusion.

Shit, we are in a really touristic place. Probably everything is really expensive around here.

The problem is we are starving, as it is already 3PM, and for sure lunch is not gonna be here. We are gonna try to

find a Paladar (private family owned restaurant) to have lunch.

Cheap food in a Paladar. Let´s see, because some of them are expensive. Usually they cost 30 Cuban Pesos.

That one is one of those expensive Paladars I was talking about. It costed 9 to 18 CUCs, we are used to pay around 1 CUC.

One more thing we just realised here is the safety of Cuba. Take a look at my camera. Actually, some time

ago the camera was even out of this case. I was walking all around with it and the locals told us that here is safe.

Teresa, the owner of our accommodation, told me that one tourist that was staying at her house got robbed.

When she told me that, I thought she was talking about armed robbery, but she told me that those things do not

exist in Cuba. What happened is that he was really drunk and some people pickpocked him.

So, it is really safe to travel here in Cuba.

Raining a lot. We are trying to get a taxi to a club.

- We managed to get the taxi and tonight we are gonna... - Go party!!

So we came to Fábrica de Arte, which everyone says it is cool, but it is looking really "cult". I am not seeing anyone

drinking, I am not seeing people drunk, partying, dancing. I am not seeing anyone dancing. - But it looks cool!

I am talking to the camera, by the way.

Drinking a revolutionary beer in a fancy bar. Bullshit. It is a Heineken!!

For more infomation >> Havana Vieja e Balada - EP 03 - Duration: 14:05.

-------------------------------------------

Youtube channel dedicated for photographers who love Nature - Duration: 3:03.

Hello and welcome on Waterfalls of France

Today I am in Auvergne

in the 'Alpes Maritimes'

in Paris

in 'Var'

in 'Nièvre'

in 'Jura'

In 'Ariège'

in 'Tarn'

in the 'Vosges'

Waterfalls of France

I think that taking pictures is not only doing one click

It's a discovery

in adventure

because it's a blink

a moment that will never be again

only photo does that

Whatever the place

the picture will always be unique

The waterfalls are beautiful and there are a lot of them in France

but they are only alibis to discover new horizons

to take pictures

We will not look for awesomeness here, like shooting the highest waterfall

do the longest exposure ever

or talk about the latest best gears

here, it"s the instant which counts

the instant you know

when you click and the emotion grows

For all who loves those moments

the fex seconds before taking the shot

when you know that everything fits

when the light is good

and you know that the picture will be nice

this is photography

the time stops

and we all feel that moment

even if we are beginners, amateurs or pros

whether we do portraits or landscapes

photography takes us

pushes us always further

you do not have to do 1000 of km to see nice places

France is full of beautiful places

et us photographers

see them, and try to capture them

thanks to new plateforms

it is now possible to share

to discover together these nice places

This Youtube channel

enables to discover those beautiful places

and share on what we discovered

Waterfalls of France will be built together

I think that taking picture is not only clicking

it's a passion that bring us high

Let's share together

Waterfalls of France

For more infomation >> Youtube channel dedicated for photographers who love Nature - Duration: 3:03.

-------------------------------------------

Genius Uses Drone as Delivery Vehicle for KFC Pick Up - Duration: 1:18.

For Complex News, I'm Hanuman Welch

We've all been there too hungry to get up and too lazy to reach for your phone, what's

the solution?

Well if you're New Zealand's Ollie Mason-Clarke, you use the same technology the defense industry

uses to solve its problems.

Clarke wanted KFC but was nowhere near a KFC and since they don't deliver he retro-fitted

a drone into a fried chicken delivery system Clarke,runs the website King of Cheat Meals

and he made arrangements with a local KFC branch and then flew his drone across town

to pay for a meal and pick it up in the drive-through lane.

Sadly, the drone wasn't able to carry an entire bucket of chicken back.

But he did end up with enough food for him and his friend, and he didn't even have to

leave his table in the park to get it.

Now, for those of you out there who may be skeptical by all of the viral marketing stunts

that companies have pulled off in the past, Mason-Clarke insists that wasn't the case

here.

Thats' all for now, but for everything else subscribe to Complex on YT, for Complex News

I"m Hanuman Welch.

For more infomation >> Genius Uses Drone as Delivery Vehicle for KFC Pick Up - Duration: 1:18.

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Why Hollywood Won't Cast Jennifer Hudson Anymore - Duration: 4:34.

Jennifer Hudson, the loveable girl-next-door with a powerhouse voice, was enjoying a sensational

rise to fame 10 years ago.

Despite not making the quarterfinals of American Idol in 2004, she still managed to carve out

a promising career.

Hudson even went on to star as Effie in the hit movie Dreamgirls, and won an Oscar for

Best Supporting Actress.

Nothing seemed to stop the Chicago native, and her debut album won a Grammy for Best

R&B album in 2009.

"I always call it a blessing and a curse."

"Yes."

"Because everything has to live up to those expectations of the Oscar, the Grammy, of

a Dreamgirls, of..

And I'm telling you, Jesus, ha.."

However, her fame has faded over the past few years, leading some to wonder how such

a talented performer has could ever not be on the A-list.

Here are a few reasons why her career might've stalled.

From huge hits to massive flops

Fresh from her Oscar-winning performance in Dreamgirls, Hudson went on to star in huge

hits Sex and the City and The Secret Life of Bees.

However, that same year she landed a role in Fragments, a straight-to-DVD flop that

starred Forest Whitaker.

Hudson's next project was the biopic Winnie Mandela, which was hit with controversy when

Winnie herself wanted production on the film shut down.

Hudson's movie career never recovered and after trying her hand with comedy in the critically-panned

The Three Stooges and then appearing in the musical drama Black Nativity.

It seems casting agents started to avoid her declining star power.

The family tragedy that shook the world

In October 2008, while celebrating her debut solo album success, Jennifer Hudson was rocked

by the news her 57-year-old mother Darnell Donerson and her 29-year-old brother Jason

had been murdered at their home in Chicago.

Local and national news outlets reported her 7-year-old nephew Julian King was reported

missing, but was later found dead in an abandoned vehicle.

William Balfour, the estranged husband of Hudson's sister Julia and father of Julian,

was arrested and charged with the murders, and sentenced in 2012 to life imprisonment.

Although none of this was Hudson's fault, the tragic events surrounding her family certainly

changed the narrative about the singer-actress.

It's possible that these terrible crimes may have distracted studios and audiences from

her formidable talents and screen skills.

A whole new role

Jennifer Hudson got engaged to David Otunga, a former pro-wrestler in the WWE, in 2008

and in 2009, she announced the couple was expecting their first child together.

Despite being pregnant, Jennifer continued with her workload and even went on tour with

Robin Thicke in May.

However, she disappointed fans after later cancelling tour dates due to "throat fatigue."

Hudson gave birth to David Junior just two months later in August 2009, and fell off

the celebrity radar by taking time off to focus on being a mother.

Diet diva

Hudson took it easy after the birth of her first child, and rightly so.

However, her failure to land movie roles or release music didn't go unnoticed by Hollywood,

and her fame began to dissipate.

She looked to get back into the limelight by becoming the face of Weight Watchers in

2010, and told Oprah Winfrey she had lost 56 pounds and didn't plan on losing any more.

However, fans were concerned for her well-being after she debuted a very slim figure in February

2011, revealing she had lost a total of 80 pounds.

Losing the musical muscle

Jennifer Hudson released her second album, I Remember Me, in 2011, and it debuted on

the Billboard 200 chart at number two.

However, only one single, "Where You At," was a hit.

Hudson later reinvented herself for her next studio release.

With a new haircut and edgier style, she enlisted the help of Timbaland and Pharrell Williams

for her third album, JHUD in 2014.

Disappointingly, it was a flop, selling a mere 24,000 copies in the first week of its

release — a significantly lower figure than the 165,000 that her previous album had sold

in its first week.

Billboard even suggested her Oscar win in 2009, and her focus on becoming a brand, was

damaging her music career.

Taking the stage

Shaking off her music career failures, Hudson focused on acting.

With her powerful voice and focused determination, it was no surprise when she made her Broadway

debut with a role in the hugely successful revival of The Color Purple in 2015.

However, she later accused the production of casting her just because she was a celebrity,

seemingly affecting her chances of being cast again in a Broadway show.

Hudson went on to carve out a TV career, guest starring in Lee Daniels' TV show Empire in

2015, and later playing Motormouth Maybelle in NBC's Hairspray Live! in 2016.

Time for a turnaround

If anyone can overcome adversity, it's Jennifer Hudson.

"Know that whether you win or not you still have the prize which is your talent and you

can still make it."

And it looks like she's ready to make a real career resurgence now.

She signed to Epic Records in 2016 and plans to release her fourth studio album soon.

She also landed a role opposite Adam Sandler in the Netflix comedy Sandy Wexler.

The former American Idol star has also returned to her talent show roots, becoming a judge

on the U.K. version of The Voice, alongside will.i.am, Tom Jones and Gavin Rossdale.

In other words, her career is still very much in play, even if she's still not quite reaching

greatest hits status at the moment.

Give it time.

"I worked for that, okay?!"

Thanks for watching!

Click the Nicki Swift icon to subscribe to our YouTube channel.

Plus check out all this cool stuff we know you'll love, too!

For more infomation >> Why Hollywood Won't Cast Jennifer Hudson Anymore - Duration: 4:34.

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En Dürüst Cevap Ver (#Videom) - Duration: 5:45.

For more infomation >> En Dürüst Cevap Ver (#Videom) - Duration: 5:45.

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Segmentação do metabolismo das células cancerígenas - Duration: 5:41.

Alvejando o Metabolismo de Células Cancerígenas

Animação: Arkitek Scientific

Apoio financeiro: FORMA Therapeutics.

O câncer é causado pela proliferação descontrolada de células.

Células cancerígenas são famintas.

Para conseguir atender a demanda de nutrientes e blocos de construção de células,

que permite a elas crescer e se multiplicar rapidamente,

o metabolismo dessas células muda.

Novos insights sobre esses processos têm gerado interesse no desenvolvimento de remédios

que visam as características metabólicas únicas das células cancerígenas.

Esses medicamentos têm potencial para tratar cânceres

que ocorram em vários tecidos diferentes,

enquanto deixam as células normais relativamente intactas.

O metabolismo modificado das céluas cancerígenas envolve

um aumento da absorção de nutrientes como glicose e glutamina.

Elas também passam a metabolizar a glicose de uma forma levemente diferente;

um fenômeno chamado "Efeito Warburg".

Em todas células, a glicose é quebrada em várias etapas

produzindo piruvato.

Em células normais, a maior parte do piruvato entra no Ciclo de Krebs na mitocôndria,

funcionando efetivamente como uma fábrica de energia da célula.

Dessa forma, a maior parte da glicose absorvida

é totalmente oxidada, produzindo dióxido de carbono.

Na década de 1920, Otto Warburg descobriu que células cancerígenas,

ao contrário da maioria das células saudáveis,

metabolizam a maior parte de sua glicose usando vias bioquímicas

que não usam oxigênio, mesmo que ele esteja disponível.

O excesso de glicose é absorvido e, como em células normais,

quebrado em moléculas de piruvato.

No entanto, ao invés de entrar no Ciclo de Krebs,

a maior parte do piruvato é convertida em lactato,

que é expelido da célula.

Ainda existem dúvidas sobre o motivo de tumores usarem

esse modo relativamente ineficiente de extrair energia da glicose.

Uma tese é de que o processo reflete uma programação metabólica

que células usam para converter nutrientes em blocos de construção de macromoléculas.

Células podem ser vistas como fábricas moleculares.

E a glicólise não é o único aspecto do metabolismo celular

que resulta em células cancerígenas.

Células cancerígenas passam por uma troca geral,

indo de metabolismo catabólico para anabólico,

para que consigam produzir a quantidade bem maior de proteínas,

ácidos nucleicos e líquidos que precisam para garantir

suas altas taxas de proliferação.

Células cancerígenas também absorvem aminoácidos.

Dentre eles, a glutamina tem uma importância particular:

ela age como uma fonte-chave de nitrogênio,

que é necessário para síntese de nucleotídeos e novos aminoácidos.

Em algumas células cancerígenas, a glutamina também age como uma fonte crítica

de carbono, que é necessário para reabastecer os componentes do Ciclo de Krebs.

Muitos medicamentos contra o câncer no mercado possuem alvos metabólicos nas células.

Mesmo que, para uma boa parcela deles,

os alvos só tenham sido reconhecidos bem depois do desenvolvimento dos remédios.

Por exemplo, remédios amplamente usados em quimioterapia,

como 5-fluorouracil e gencitabina,

interferem na síntese de DNA.

Atualmente, há uma multidão de abordagens em desenvolvimento,

que visam diferentes aspectos do metabolismo de células cancerígenas.

Por exemplo, cientistas estão explorando a possibilidade de bloquear a glutamina,

para interromper o fornecimento de carbono e nitrogênio.

Cientistas também consideram outras enzimas como alvo,

para limitar o uso de nutrientes na produção de blocos de construção essenciais.

Algumas estratégias visam interferir nas altas taxas

de metabolismo de glicose e secreção de lactato descritas por Otto Warburg.

Abordagens anti-câncer alvejando metabolismo de tumores

encaram muitos desafios.

O principal é encontrar a janela terapêutica

para prevenir que o tecido normal seja atingido.

No entanto, tem ficado claro que as mudanças genéticas associadas ao câncer

podem criar inclinações ao uso de vias metabólicas específicas

que podem ser exploradas em um tratamento.

Além disso, células cancerígenas podem ser mais sensíveis

a perturbações metabólicas do que células normais,

devido à perda de alguns checkpoints de ciclos celulares.

Uma melhor compreensão de como o metabolismo é alterado

em contextos genéticos específicos que levam ao câncer,

ajudará cientistas a identificar enzimas ou combinações de enzimas

que possam ser alvejadas para intervenção.

E provavelmente permitirá a criação de medicamentos mais eficientes para combater o câncer.

For more infomation >> Segmentação do metabolismo das células cancerígenas - Duration: 5:41.

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Cubic Castles not working - Duration: 2:31.

Hello guys . sorry for not uploading any cubic castles video's coz

my cubic castles is not working

its keep on showing me this

so i thought i should verify the game then maybe it work's...

but still not working .........

then i try'ed to delete the game & download it again then it should work right?.....

but as u can see still showing me this .... also i try'ed sending report and yet not working .....

so guy's maybe this will be my last cubic castles video

also if u wanna see me play some other game's like creativerse then let me know by comment..

For more infomation >> Cubic Castles not working - Duration: 2:31.

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زرق ورق ثري الحلقة الاولى كاملة HD - Duration: 25:15.

ترجمة

For more infomation >> زرق ورق ثري الحلقة الاولى كاملة HD - Duration: 25:15.

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الفلم الروسي المال من اجل البنت - Duration: 1:34:47.

For more infomation >> الفلم الروسي المال من اجل البنت - Duration: 1:34:47.

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Chicken | Colours Chicken | Paintings Chicken | Chicken Coloring Book - Duration: 3:31.

Hello

For more infomation >> Chicken | Colours Chicken | Paintings Chicken | Chicken Coloring Book - Duration: 3:31.

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3 Awesome Life Hacks or Ideas - Duration: 15:35.

For more infomation >> 3 Awesome Life Hacks or Ideas - Duration: 15:35.

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🔴Viajando en la Galaxia de Warframe🔴 - Duration: 1:52:50.

For more infomation >> 🔴Viajando en la Galaxia de Warframe🔴 - Duration: 1:52:50.

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WE TRIED TO SPEAK JAPANESE / Blue And Green - Duration: 5:15.

Hello girls, how are you?

(Translator)

What?

This is our new intro

Just ... Just missing the "are you focusing?"

(Translator)

Green: Half an hour to talk Blue: Are you focusing?

So we'll get into the "modinha"

And will try to speak another language

We chose Japanese

Because we want to know if we talk right.

I think we're going to talk a lot of shit.

Phrase 1 Hi girls, how are you?

(Translator)

I can't

Can not say "Hello girls, how are you?"

Phrase 2 How much does this cost?

I think is that

Phrase 3 What is your name?

I can't say that. We don't ask the name of the person

We use English because...

Phrase 4 I'm hungry!

Looks like you're speaking "yummy" in Korean

I am fluent in Japanese (irony)

Phrase 5 Are you focusing?

Is that?

Phrase 6 I like Naruto

Phrase 7 Potato is very good

We cannot say that the potato is good

No... And even though we're hungry...

Is very difficult

Ah... I don't like potato

That's it. Thank you for watching the video.